Control of bisphosphonate release using hydroxyapatite granules

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Control of bisphosphonate release using hydroxyapatite granules.

The efficacy of hydroxyapatite (HAp) as a carrier was investigated to establish a method of local administration of bisphosphonates (Bps), which has currently been administered systemically. HAp granules (300-500 microm in size) with different physicochemical features were prepared by altering the sintering temperature. To ascertain the physicochemical properties of the HAp granules, their crys...

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ژورنال

عنوان ژورنال: Journal of Biomedical Materials Research Part B: Applied Biomaterials

سال: 2006

ISSN: 1552-4973,1552-4981

DOI: 10.1002/jbm.b.30446